Mateon Therapeutics (MATN) vs. Affymax (AFFY) Head to Head Contrast

Affymax (OTCMKTS: AFFY) and Mateon Therapeutics (NASDAQ:MATN) are both small-cap medical companies, but which is the superior stock? We will contrast the two companies based on the strength of their dividends, earnings, valuation, risk, profitability, institutional ownership and analyst recommendations.

Analyst Recommendations

This is a breakdown of recent recommendations and price targets for Affymax and Mateon Therapeutics, as provided by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Affymax 0 0 0 0 N/A
Mateon Therapeutics 0 1 3 0 2.75

Mateon Therapeutics has a consensus price target of $2.00, suggesting a potential upside of 483.98%. Given Mateon Therapeutics’ higher probable upside, analysts plainly believe Mateon Therapeutics is more favorable than Affymax.

Insider & Institutional Ownership

8.6% of Mateon Therapeutics shares are owned by institutional investors. 1.6% of Affymax shares are owned by insiders. Comparatively, 2.3% of Mateon Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

Volatility & Risk

Affymax has a beta of 2, indicating that its share price is 100% more volatile than the S&P 500. Comparatively, Mateon Therapeutics has a beta of 1.53, indicating that its share price is 53% more volatile than the S&P 500.


This table compares Affymax and Mateon Therapeutics’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Affymax N/A N/A N/A
Mateon Therapeutics N/A -224.38% -186.53%

Earnings and Valuation

This table compares Affymax and Mateon Therapeutics’ gross revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio EBITDA Earnings Per Share Price/Earnings Ratio
Affymax $41,999.00 41.06 -$47.65 million N/A N/A
Mateon Therapeutics N/A N/A -$14.59 million ($0.54) -0.63

Mateon Therapeutics has higher revenue, but lower earnings than Affymax.


Mateon Therapeutics beats Affymax on 5 of the 9 factors compared between the two stocks.

About Affymax

Affymax, Inc. is a biopharmaceutical company. The Company’s product OMONTYS (peginesatide) is for the treatment of anemia due to chronic kidney disease in adult patients on dialysis. OMONTYS is a synthetic, peptide-based erythropoiesis stimulating agent (ESA), designed to stimulate production of red blood cells. The Company has a collaboration to develop and commercialize peginesatide with Takeda Pharmaceutical Company Limited. In March 2012, the Food and Drug Administration (FDA) approved the Company’s product, OMONTYS.

About Mateon Therapeutics

Mateon Therapeutics, Inc., formerly OXiGENE, Inc., is a biopharmaceutical company. The Company is focused on the development of vascular disrupting agents (VDAs) for the treatment of cancer. The Company is engaged in developing two clinical stage investigational drugs: VDAs-CA4P and OXi4503. Its lead compound is CA4P, which is also known as combretastatin A4-phosphate, fosbretabulin tromethamine, fosbretabulin and ZYBRESTAT. VDAs selectively targets the vasculature of cancer tumors and obstructs a tumor’s blood supply without disrupting the blood supply to normal tissues. VDAs are in a class of drugs called vascular targeted therapies (VTTs), which also includes anti-angiogenic agents (AAs). CA4P is a reversible tubulin binding agent that selectively targets the endothelial cells that make up the blood vessel walls in solid tumors. The Company is pursuing the development of a product candidate, OXi4503, which is a dual-mechanism VDA.

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